- The Amalekites are a people mentioned a number of times in the Hebrew Bible. They are considered to be descended from an ancestor Amalek. According to the Book of Genesis and 1 Chronicles, Amalek was the son of Eliphaz and the grandson of Esau (Gen. 36:12; 1 Chr. 1:36); the chief of an Edomite tribe (Gen. 36:16). His mother was a Horite, a tribe whose territory the descendants of Esau had seized. According to the genealogy in Gen. 36:12; 1 Chr. 1:36. Amalek is a son of Esau's son Eliphaz and of the concubine Timna, a Horite and sister of Lotan.